Selective Synthesis of Oligosaccharides by Mechanochemical Hydrolysis of Chitin over a Carbon‐Based Catalyst

Oligosaccharides possess fascinating functions that are applicable in a variety of fields, such as agriculture. However, the selective synthesis oligosaccharides, especially chitin-oligosaccharides, has remained challenge. Chitin-oligosaccharides activate plant immune system, enabling crops to withstand pathogens without harmful agrichemicals. Here, we demonstrate conversion chitin chitin-oligosaccharides using carbon catalyst with weak acid sites and mechanical milling. The produces up 94 % selectivity good yields. Monte-Carlo simulations indicate our system preferentially hydrolyzes larger molecules over oligomers, thus providing desired high selectivity. This unique kinetics is contrast fact typical catalytic systems rapidly hydrolyze oligomers monomers. Unlike other materials carbons more strongly adsorb large polysaccharides than small which suitable for oligosaccharides.